WATER SYSTEMS SOLUTION FOR ONDERSTEPOORT BIOLOGICAL PRODUCTS (OBP)

RFI/OBP003/2026/27

Vendors must specify how their designs meet the following standards: Criteria Potable Bulk Storage PW / WFI Storage Material High-density polyethylene (HDPE) or Epoxy-coated Carbon Steel 316L Stainless Steel (controlled sulfur content) Surface Finish Standard industrial food-grade Electropolished internal surfaces (\(R_a \leq 0.38\ \mu\text{m}\) or \(0.2\ \mu\text{m}\)) Geometry Vertical cylindrical or modular sectional Vertical, jacketed, fully drainable, crevice-free Sanitization Chemical (Chlorination/UV dechlorination) Continuous hot looping (\(\ge 80^{\circ }\text{C}\) steam jacket) or Ozone Contamination Control & Loop Integration For pharmaceutical-grade holding tanks, please detail options for: • Vent Filtration: Hydrophobic, sterile-grade, gas-retentive vent filters with integrated heating jackets to prevent condensate blockages. • Blanketing: Nitrogen or sterile compressed air head-space blanketing. • Spray Devices: Fixed or retractable Clean-In-Place (CIP) spray balls ensuring 100% wetting coverage. Vendor Information Requested Company Capability & References • Provide brief evidence of previous installations in cGMP, WHO-prequalified, or FDA-regulated vaccine/biologics production settings. • List standard delivery lead times for manufacturing and site assembly. Technical System Description • Submit general assembly drawings (2D/3D templates) for both bulk raw water and sanitary storage blocks. • Detail the automation architecture (e.g., PLC/SCADA integration) for real-time level, conductivity, TOC, and temperature monitoring. Water Conservation & Recirculation Options • Describe how your system maintains constant turbulent flow during prolonged holding to prevent biofilm growth. • Detail any integrated water recycling or reject-recovery mechanisms within the pretreatment loop

Request for Information

2026/07/02 15:30:00

2026/06/25 12:00:00

RFI/OBP003/2026/27